Research projects

Unraveling molecular mechanism and metabolic consequences of ERK3/MK5 action in beige and brown adipocytes

Testing the impact of ERK3 in skeletal muscle on development of obesity, T2D, dynapenia and sarcopenia.

Identification of molecular and metabolic consequences of ERK3 action in skeletal muscles

Developing and testing ERK3 and MK5 inhibitors for treatment of obesity, T2D, dynapenia and sarcopenia

Identification of mechanisms of Erk3-mediated regulation of lipolysis and its impact on development of obesity and T2D

Identification and characterization of novel signaling molecules promoting lipolysis during cancer-associated cachexia (CAC)

Identification of novel, non-canonical signaling modules (E3 ligases and DUBs) in the regulation of Erk3-dependent and independent lipolysis

Unraveling molecular mechanism and metabolic consequences of ERK3/MK5 action in beige and brown adipocytes

Test the impact of ERK3 in skeletal muscle on development of obesity, T2D, dynapenia and sarcopenia

Identifying molecular and metabolic consequences of ERK3 action in skeletal muscles

Developing and testing ERK3 and MK5 inhibitors for treatment of obesity, T2D, dynapenia and sarcopenia

Identification of cellular and molecular mechanism of Pkds' action in adipocytes 

Uncovering Pkds’ functions in the regulation of liver metabolism

Defining cellular and molecular mechanisms of Pkd2-mediated lipid absorption in intestines and verifying the therapeutic potential of targeting this kinase

Identification of novel, non-canonical signaling modules (phosphatases, E3 ligases and DUBs) in the regulation of Pkd-dependent and independent lipid metabolism